Research Article, J Pharm Sci Emerg Drugs Vol: 4 Issue: 1
An In Vitro Study of Binding of Aceclofenac and Pantoprazole with Bovine Serum Albumin by UV Spectroscopic Method
| Sabiha Ferdowsy Koly1, Md. Zakir Sultan2, Asma Rahman2, Shaila Kabir1 and Mohammad Shah Amran1* | |
| 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh | |
| 2Centre for Advanced Research in Sciences, University of Dhaka, Dhaka-1000,Bangladesh | |
| Corresponding author : Md. Shah Amran Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh Tel: +8801718617915 E-mail: amranms@du.ac.bd |
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| Received: May 22, 2015 Accepted: December 29, 2015 Published: January 04, 2016 | |
| Citation: Koly SF, Sultan Md.Z, Rahman A, Kabir S, Amran MS (2016) An In Vitro Study of Binding of Aceclofenac and Pantoprazole with Bovine Serum Albumin by UV Spectroscopic Method. J Pharm Sci Emerg Drugs 4:1 doi:10.4172/2380-9477.1000109 |
Abstract
An In Vitro Study of Binding of Aceclofenac and Pantoprazole with Bovine Serum Albumin by UV Spectroscopic Method
Plasma protein binding is one of the most important pharmacokinetic parameter of drug. The study was designed to determine the binding of Aceclofenac and Pantoprazole to Bovine Serum Albumin. The study was conducted by equilibrium dialysis method followed by measurement using a spectrophotometer at pH 7.4 and 37°C
