Infection Control and Clinical Microbiology 2017 - Antibiotic-impregnated central venous catheters for the prevention of catheter-related bloodstream infection in children: A meta-analysis

Use of valuable venous catheters (CVCs) make certain strong get right of entry to in critically ill sufferers but is related to increased infection rates. CVCs with antimicrobials has been recommended for contamination reduction in adults. A evaluation of antibiotic-impregnated CVCs’ usefulness in children is needed. Catheter-related bloodstream infections have a first-rate impact on increasing health care fees and morbidity and mortality in hospitalized sufferers. Many technologies were created in an try and decrease the incidence of catheter-associated bloodstream contamination. One of those is the impregnation of significant venous catheters with antiseptics (e.G., chlorhexidine and silver sulfadiazine) or antibiotics (e.G., minocycline and rifampin). While research comparing the efficacy of impregnated catheters had been conducted, the data are constrained and their use stays variable throughout institutions. This paper will talk catheter-related elements that predispose patients to catheter-associated bloodstream contamination, the kinds of antimicrobial-impregnated catheters in use today, research evaluating their efficacy, and commonplace concerns related to the use of these catheters. Issues associated with the cost-effectiveness of impregnated catheters and future recommendations for the prevention of catheter-related bloodstream contamination also can be presented.