Research Article, J Appl Bioinform Comput Biol Vol: 4 Issue: 1
Semi-Automated Image Processing for Preclinical Bioluminescent Imaging
Nikolai V Slavine1* and Roderick W McColl2 | |
1Department of Radiology, Division of Translational Research, UT Southwestern Medical Centre, Dallas, USA | |
2Department of Radiology, Division of Clinical Medical Physics, UT Southwestern Medical Centre, Dallas, USA | |
Corresponding author : Nikolai V Slavine Department of Radiology, Division of Translational Research, UT Southwestern Medical Center, Dallas, USA Tel: 214-648-9196; E-mail: nikolai.slavine@southwestern.edu |
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Received: December 16, 2014 Accepted: March 06, 2015 Published: March 13, 2015 | |
Citation: Slavine NV, McColl RW (2015) Semi-automated Image Processing for Preclinical Bioluminescent Imaging. J Appl Bioinform Comput Biol 4:1. doi:10.4172/2329-9533.1000114 |
Abstract
Semi-automated Image Processing for Preclinical Bioluminescent Imaging
Small animal bioluminescence imaging (BLI) is used to observe noninvasively and in real time the presence or activation of specific biological process at the molecular level. With a multi-camera BLI device capable of tomographic studies, the 3D spatial distribution and temporal dynamics of luciferase expressing cells within the animal can be measured in great detail.