Research Article, J Pharm Sci Emerg Drugs Vol: 3 Issue: 1
The Effect of the Antioxidant Drug 'U-74389G' on Uterus Inflammation during Ischemia Reperfusion Injury in Rats
| Τsompos C1*, Panoulis C2, Τοutouzas K3, Ζografos G4 and Papalois A5 | |
| 1Department of Obstetrics & gynecology, Mesologi County Hospital, Etoloakarnania, Greece | |
| 2Department of Obstetrics & gynecology, Aretaieion Hospital, Athens University, Attiki, Greece | |
| 3Department of Surgery, Ippokrateion General Hospital, Athens University, Attiki, Greece | |
| 4Department of Surgery, Ippokrateion General Hospital, Athens University, Attiki, Greece | |
| 5Exprerimental Research Center ELPEN Pharmaceuticals, S.A. Inc., Co., Greece | |
| Corresponding author : C. Τsompos Department of Obstetrics & Gynecology, Mesologi County Hospital, Etoloakarnania, Greece Tel: +3026310 57100; Fax: +3026310 57107 E-mail: constantinostsompos@yahoo.com |
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| Received: August 27, 2014 Accepted: March 12, 2015 Published: March 16, 2015 | |
| Citation: Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A (2015) The Effect of the Antioxidant Drug “U-74389G” on Uterus Inflammation during Ischemia Reperfusion Injury in Rats. J Pharm Sci Emerg Drugs 3:1. doi:10.4172/2380-9477.1000107 |
Abstract
This experimental study was to examine the effect of the antioxidant drug “U-74389G”, on rat model and particularly in a uterus ischemia reperfusion (IR) protocol. The beneficial effect or non-effectiveness of that molecule were studied pathologically using uterus inflammation (UI) lesions.40 rats of mean weight 231.875 gr were used in the study. UI lesions were evaluated 60 min after reperfusion (groups A and C) and 120 min after reperfusion with administration of the drug U-74389G in groups C and D.
